Antibiotic resistance is a topic that is increasingly high on the agenda of most healthcare professionals across the world- and with good reason. The profligate use of antibiotics is set to result in up to 10 million deaths every year by 2050, costing the global economy an astonishing £65 trillion. Whilst efforts are being made to minimise the emergence of superbugs, antibiotic resistant strains of bacteria continue to foster a global health crisis, posing a serious threat to hospital patients. These have more recently included carbapenemase-producing Enterobacteriaceae (CPE).
CPE encompasses a range of bacteria, including Escherichia, Klebsiella, Shigella and Salmonella to name but a few. While many of the species reside harmlessly in the human gut, these bacteria have an ability to produce enzymes which are deadly to most antibiotics (carbapenems), making them extremely difficult to treat should they manifest as bloodstream infections. Hospital patient mortality rates are currently between 40-50%, lending to CPE’s alarming title of ‘seriously emerging infectious disease’.
Reports of CPE are currently prevalent in Asia, afflicting countries such as India, Bangladesh, Pakistan, the Middle East, China, Taiwan and Japan. Infection has also been documented in the USA, as well as some of southern Europe. In February 2017, the World Health Organisation branded carbapenem resistant bugs a “critical priority” and stressed the need for effective antibiotics.
So, what can be done to halt the impending rise of these practically ‘untreatable’ superbugs?
We’ve said it once, we’ll say it a thousand times: thorough hand-washing practices and cleaning routines are essential in infection control. However, they are not enough in isolation.
BioCote® Antimicrobial Technology is effective against a wide range of superbugs, including carbapenemase-producing Enterobacteriaceae, destroying up to 99.99% of the bacteria through protein and oxidative damage, membrane disruption and DNA interference. We have a complete range of additives to suit any material application, including polymers, coatings, textiles, paper, ceramics and many more. Our technology can be cost-effectively introduced during the manufacturing process, providing the highest levels of antimicrobial protection for the functional lifetime of your product and supporting existing hygiene processes.
For more information on how BioCote® Technology can be incorporated into your product(s), please contact us today.